99% Purity Dexamethasone Powder for Allergies CAS: 50-02-2 Hot Sale Hormone for Anti-Inflammatory
Quick Detail:
Synonyms: 16alpha)-;16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet;16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-2,20-dione;16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2;16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione;16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-dien;16alpha-Methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione;16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Chemical Properties White Crystalline Solid
Boiling Point: 568.2 °C at 760 mmHg
Vapour Pressure: 2.81E-15 mmHg at 25 °C
Melting point: 262-264 °C
Storage tempreture: 2-8 °C
Density: 1.32 g/cm3
Solubility: Ethanol: 1 mg/mL
Flash Point: 297.5 °C
Appearance: White crystalline solid
Description:
Dexamethasones is a synthetic corticosteroid with approximately 25 times the anti-inflammatory potency of naturally occurring cortisol. The IUPAC Name of it is (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl6,7,8,11,12,14,15, octahydrocyclopenta[a]phenanthren-3-one. Dexamethasones commonly is used in both small- and large-animal veterinary medicine. It may be given by injection, inhalation orally or topically. Preparations for topical use may include other active ingredients such as antibiotics, antifungals or miticides.
COA:
| Test Items |
Specification |
Test Results |
| Appearance |
white oralmost white,crystalline powder |
Conform |
| Solubility |
Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride. |
Conform |
| Identification |
A |
The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64. |
Conform |
| B |
Infraed absorption spectrophotometry. |
Conform |
| C |
Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. |
Conform |
| D |
An orange-red color develop in methylene chloride layer. |
Conform |
| E |
It geves reaction (a) of sulphates. |
Conform |
| Appearance of solution |
Solution S is clear and not more intensely coloured than reference solution in BY6. |
Conform |
| Optical rotation |
-0.10° to +0.10°determined on solution S. |
+0.01° |
| Acidity or alkalinity |
NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. |
Conform |
| Related substances |
Impurity J ≤0.20% |
Conform |
| Any other impurity ≤0.30% |
Conform |
| Total impurity ≤1.0% |
Conform |
| Boron |
≤50ppm |
Conform |
| Sulphated ash |
≤0.10% |
0.06% |
| Loss on drying |
≤0.5% |
0.30% |
| Assay(on dried basis) |
98.0~101.0% |
98.8% |
| Conclusion |
The test results above BP2009 |
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